The San Diego 500, The Book of Influential Business Leaders, is the market’s most comprehensive product of people you should know in the business community. The 500 includes business leaders and executives who have founded or are running significant companies in terms of number of jobs, key products and services, experts who raise the level of the industry here and beyond and those who lead in the business community. The 500 is selected by the San Diego Business Journal newsroom.

Kleanthis Xanthopoulos

President and CEO, Irras

Kleanthis Xanthopoulos is a serial entrepreneur in biotechnology who recently took a third company public – Irras, a neurosurgery device company, in this case on the NASDAQ Stockholm First North Premier market. Xanthopoulos served as founding CEO of Regulus Therapeutics from 2007-2015. He also serves as managing general partner of Cerus DMCC, an investment firm. His diverse background also includes time in academia and venture capital. He has been honored as EY Entrepreneur of the Year and by the SDBJ as Most Admired CEO.

ALMA MATER: Aristotle University of Thessaloniki, Greece; University of Stockholm, Sweden

PASSION: Soccer

FAVORITE GET-AWAY: Greece

TOUGHEST CHALLENGE: Overcoming two cardiac arrests resulting from a serious burning accident at an early age.

BUSINESS ADVICE: “Big results require big ambitions – Heraclitus circa 500 BC.”

EXCITED ABOUT: Translating biological information in medicines.